Concepts

All (84)Explore Concept Graph

84 concepts

measurement

metagenome-assembled genome

Genomic bins reconstructed from metagenomic sequencing data representing individual microbial taxa

molecular23 papers
theory

gene coalescence

Statistical method for recognizing evolutionarily independent lineages based on genealogical patterns in molecular data

molecular20 papers
measurement

metabarcoding

The identification of species from environmental DNA samples using target capture sequencing and database matching

molecular8 papers
measurement

molecular formula abundance

molecular7 papers
process

horizontal gene transfer

Transfer of genetic material between organisms through mechanisms other than vertical inheritance

molecular6 papers
mechanism

sex chromosomes

Chromosomes that determine sex, including different haplotypes in the sex-determining region

molecular5 papers
measurement

transcriptomics

The study of the complete set of RNA transcripts produced by the genome under specific circumstances

molecular5 papers
process

anthocyanin biosynthesis

Biochemical pathway producing anthocyanin pigments responsible for purple coloration

molecular4 papers
measurement

epigenetic clock

Age estimator based on DNA methylation levels that uses penalized regression to relate chronological age to methylation levels of individual cytosines

molecular4 papers
process

DNA methylation

A small chemical modification that occurs in most cytosines that are followed by a guanine (CpGs) in mammalian genomes, serving as an epigenetic marker.

molecular3 papers
measurement

FTICR-MS

Fourier-transform ion cyclotron resonance mass spectrometry for ultrahigh-resolution molecular characterization

molecular3 papers
methodology

genome annotation

Computational identification and labeling of genes and other functional elements in genome sequences

molecular3 papers
measurement

microsatellite DNA analysis

Molecular technique using highly polymorphic DNA markers to assess genetic relationships among individuals

molecular3 papers
phenomenon

mobile genetic elements

DNA sequences that can move or be transferred between different positions within genomes or between genomes

molecular3 papers
measurement

viral operational taxonomic units

Clustered viral sequences representing distinct viral taxa based on genomic similarity thresholds

molecular3 papers
measurement

BC-ratio

The proportion of aliphatic GS derived from branched-chain amino acid (Val and Ile) precursors, representing quantitative trait variation controlled by known biosynthetic locus

molecular2 papers
measurement

LTL

molecular2 papers
measurement

bioactive compounds

Chemical compounds with therapeutic or biological activity

molecular2 papers
process

brain-gut axis

Communication between the central and enteric nervous systems as a potential mechanism for microbiome-behavior relationships

molecular2 papers
framework

comparative genomics

Approach to compare genome features across multiple species to identify conserved and variable elements.

molecular2 papers
measurement

differential gene expression

Genes that show significantly different expression levels between treatment conditions

molecular2 papers
measurement

heat shock proteins

Molecular chaperones that help cells cope with protein folding stress under adverse conditions

molecular2 papers
measurement

metabolomes

molecular2 papers
process

rolling circle amplification

DNA amplification technique that amplifies circular DNA templates using phi29 DNA polymerase

molecular2 papers
measurement

AgeAccel

molecular1 paper
metric

AgeAccelClock3

molecular1 paper
framework

Angiosperms353

Universal probe set targeting 353 gene regions for phylogenomic and metabarcoding studies of flowering plants

molecular1 paper
measurement

BCMA gene

Branched Chain Methionine Allocation gene that controls ratios of glucosinolate types in Boechera stricta

molecular1 paper
methodology

CRISPR gene editing

A gene-editing technology that allows precise modification of DNA sequences

molecular1 paper
process

CRISPR targeting

Method for identifying host-pathogen relationships through sequence identity between CRISPR spacers and target genomes

molecular1 paper
phenomenon

CRISPR-Cas systems

Adaptive immune systems in prokaryotes that provide resistance against mobile genetic elements

molecular1 paper
phenomenon

Candidate Phyla Radiation

Bacteria from phyla lacking isolated representatives that consistently increase in abundance with depth

molecular1 paper
framework

Candidate Phyla Radiation (CPR)

molecular1 paper
metric

DNAmGran

molecular1 paper
framework

DPANN group

molecular1 paper
process

Ehrlich pathway

Three-step biochemical process of transamination, decarboxylation, and reduction that converts amino acids to higher alcohols

molecular1 paper
process

FOXO transcription factor

A transcription factor that controls expression of genes that mediate the negative effects of reduced IIS and is restricted from the nucleus when phosphorylated by Akt

molecular1 paper
metric

Firmicutes-Bacteroidetes ratio

Relative abundance of two major bacterial phyla associated with obesity and leanness respectively

molecular1 paper
method

Hidden Markov Models

Statistical models used to identify and characterize gene functions from metagenomic sequences

molecular1 paper
process

MHC class II

Major histocompatibility complex genes involved in antigen presentation and immune response

molecular1 paper
process

PRC2-binding

molecular1 paper
measurement

cardenolide

molecular1 paper
phenomenon

circular single-stranded DNA viruses

Small DNA viruses with circular single-stranded genomes that include families like Circoviridae, Geminiviridae, and Genomoviridae

molecular1 paper
measurement

co-methylation modules

Groups of CpG sites that show similar methylation patterns across samples

molecular1 paper
process

compartment-specific gene expression

Alternative targeting of gene products to different cellular compartments through splice variants or targeting sequences

molecular1 paper
process

coronatine

A JA-mimic produced by certain strains of P. syringae that causes the plant to inhibit SA production, allowing the bacteria to increase its virulence while encountering minimal defenses

molecular1 paper
phenomenon

cross-species applicability

The ability of molecular primers developed for one species to successfully amplify in related species

molecular1 paper
measurement

cuticular hydrocarbons

Waxy compounds on insect cuticle surface used for waterproofing and chemical communication

molecular1 paper
process

cytosine methylation

molecular1 paper
process

enzyme evolution

Changes in protein catalytic function through amino acid substitutions affecting substrate specificity or activity

molecular1 paper