horizontal gene transfer
Transfer of genetic material between organisms through mechanisms other than vertical inheritance
anthocyanin biosynthesis
Biochemical pathway producing anthocyanin pigments responsible for purple coloration
DNA methylation
A small chemical modification that occurs in most cytosines that are followed by a guanine (CpGs) in mammalian genomes, serving as an epigenetic marker.
brain-gut axis
Communication between the central and enteric nervous systems as a potential mechanism for microbiome-behavior relationships
rolling circle amplification
DNA amplification technique that amplifies circular DNA templates using phi29 DNA polymerase
CRISPR targeting
Method for identifying host-pathogen relationships through sequence identity between CRISPR spacers and target genomes
Ehrlich pathway
Three-step biochemical process of transamination, decarboxylation, and reduction that converts amino acids to higher alcohols
FOXO transcription factor
A transcription factor that controls expression of genes that mediate the negative effects of reduced IIS and is restricted from the nucleus when phosphorylated by Akt
MHC class II
Major histocompatibility complex genes involved in antigen presentation and immune response
PRC2-binding
compartment-specific gene expression
Alternative targeting of gene products to different cellular compartments through splice variants or targeting sequences
coronatine
A JA-mimic produced by certain strains of P. syringae that causes the plant to inhibit SA production, allowing the bacteria to increase its virulence while encountering minimal defenses
cytosine methylation
enzyme evolution
Changes in protein catalytic function through amino acid substitutions affecting substrate specificity or activity
gene expression regulation
The cellular process by which genes are turned on or off in response to environmental stimuli or stressors
hepatitis virus transmission
The spread of hepatitis viruses between animal hosts, particularly in mammalian populations
insulin/insulin-like growth factor signaling
A conserved nutrient-sensing signaling pathway that regulates cellular metabolism, survival, proliferation, and growth as well as reproduction
long-distance signaling
Communication between plant tissues over distances that affects reproductive processes, such as between pollen tubes and ovarian tissues
lytic infection
Viral replication strategy resulting in immediate host cell lysis and viral progeny release
mTOR signaling
A nutrient-sensing pathway where mTOR kinase can be activated by amino acids and regulates cellular processes at the lysosome
phosphotransferase system
Bacterial sugar transport system that simultaneously transports and phosphorylates carbohydrates
quorum sensing
A method of cellular communication in which organisms communicate via cell-to-cell signaling, coordinating gene expression based on population density
subcellular protein localization
The spatial distribution of proteins within cellular compartments that reflects their activation state and functional activity
transcription factors
Proteins that regulate gene expression, including pluripotency factors like OCT4 and SOX2 that can affect aging processes.
xenobiotic metabolism
Biochemical processes by which insects detoxify plant secondary metabolites and other foreign compounds
